ITM2B Symposium

Schedule

Fri Jul 10 2026 at 10:00 am to 04:00 pm

UTC+01:00
Location

UCL Great Ormond Street Institute of Child Health | London, EN

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Hear about the latest advances in familial ITM2B-linked dementia research and become part of a new research network
About this Event

Welcome to the ITM2B Symposium!

How can an understudied gene teach us to fight dementia?

Hear about recent progress in clinical and pathological research, as well as developments in disease modelling. Get the opportunity to hear about the experience of living with ITM2B-associated dementia.

This is a one day symposium and will be a hybrid format (online or in-person attendance). Lunch and coffee will be provided thanks to our sponsors.

There will be opportunities for posters and flash talks.

We hope to setup a network of ITM2B researchers to aid resource sharing and opportunities for development.


Detailed agenda to follow.

Tentative program:

Arrive 9.30am for a 10am start


10.00 Welcome from Charlie Arber


10.05-10.45 Clinical and pathological perspectives session

10.10-10.40 Simon Mead (UCL) – “Around the World for the Familial British Dementia Pedigree”

10.40-11.00 Ko Woon Kim (Jeonju, Korea) – “A Korean Family with a Novel ITM2B c.800G>C Variant”

11.00-11.25 Tamas Revesz (UCL) – the pathological basis of ITM2B-dementia

11.25-12.00 ECR Datablitz (2 x Ruben, Sam)


12.00-1.00 Lunch and posters



1.00 Molecular findings

1.00-1.30 Vidal (Indiana, USA) – “Cyro-EM structures in ITM2B dementias

1.30-2-00 Lasagna Reeves (Baylor, USA) – “Tau Depletion Reduces Vascular Amyloid–Related Pathology in a Mouse Model of Familial Danish Dementia”


Short coffee break


2.20 Modelling updates

2.25-2.50 Wray (UCL) – iPSC models of ITM2B dementia

2.50-3.15 D’Adamio (Rutgers, USA) – Mouse models and interactions ITM2B

3.15-3.40 Wohlschlegel (Seattle, USA) – ONLINE: “Inherited retinal dystrophies: the role of ITM2B”


4.00-4.30 Panel discussion


Meeting supported by:


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Where is it happening?

UCL Great Ormond Street Institute of Child Health, 30 Guilford Street, London, United Kingdom

Event Location & Nearby Stays:

Tickets

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