ITM2B Symposium
About this Event
Welcome to the ITM2B Symposium!
How can an understudied gene teach us to fight dementia?
Hear about recent progress in clinical and pathological research, as well as developments in disease modelling. Get the opportunity to hear about the experience of living with ITM2B-associated dementia.
This is a one day symposium and will be a hybrid format (online or in-person attendance). Lunch and coffee will be provided thanks to our sponsors.
There will be opportunities for posters and flash talks.
We hope to setup a network of ITM2B researchers to aid resource sharing and opportunities for development.
Detailed agenda to follow.
Tentative program:
Arrive 9.15am for a 9.45am start
09.30
Arrival and coffee
09.45-09.50
Welcome
Charlie Arber (UCL, UK)
09.50-10.10
The Origin Story of the Chromosome 13 Dementias
Gordon Plant (UCL, UK)
10.10-10.30
Around the World for the Familial British Dementia Pedigree
Simon Mead (UCL, UK)
10.30-10.50
A Korean Family with a Novel ITM2B c.800G>C Variant
Ko Woon Kim (Jeonju, Korea)
online
10.50-11.10
The pathological basis of ITM2B-dementia
Tamas Revesz (UCL, UK)
11.10-11.30
Break – tea/coffee
11.30-11.45
Discoveries in diverse populations
Henry Houlden (UCL, UK)
11.45-12.00
A novel BRI2 mutation causing neurodegeneration in the absence of amyloid and tau
Anllely Fernandez (Indiana, USA)
12.00-12.15
Sam Crawford (UCL, UK)
12.15-12.30
Monoclonal IgG1 Passive Immunotherapy Modulates Vascular Amyloid in a Familial Danish Dementia Mouse
Alexandra Moreno-Garcia
12.30-12.35
IFNβ-mediated activation of human iPSC-derived microglia increases tau phosphorylation in a human forebrain organoid model of familial British dementia
Lucrezia Bruno (UCL, UK)
12.35-12.40
Regional Quantification of Microglial Burden and Morphology in Familial British and Danish Dementias
Eleanor Wheeler (UCL, UK)
12.40-12.45
Antisense Oligonucleotides as a potential gene-based therapy for Familial British Dementia
Katie Thompson (UCL, UK)
12.45-14.00
Lunch and posters
14.00-14.30
Cyro-EM structures in ITM2B dementias
Ruben Vidal (Indiana, USA)
14.30-15.00
Tau Depletion Reduces Vascular Amyloid–Related Pathology in a Mouse Model of Familial Danish Dementia
Cristian Lasagna Reeves (Baylor, USA)
15.00-15.30
iPSC models of ITM2B dementia
Selina Wray (UCL)
15.30-16.00
Inherited retinal dystrophies: the role of ITM2B
Juliette Wohlschlegel (Seattle, USA)
Online
16.00-18.00
Drinks reception
Meeting supported by:
Where is it happening?
Event Location & Nearby Stays:
GBP 0.00
