The Brighton Tumour Microenvironment Conference - 21st-22nd October 2024

- Barts Cancer Institute, Queen Mary University of London, UK

- University of Edinburgh, UK

Dr Robyn Broad and Dr Martin Isabelle - Adaptimmune, Abigdon, UK

- University of Glasgow, UK

- University of Crete, Heraklion, Greece

- East Sussex Healthcare NHS Trust, UK

- Norwegian University of Science and Technology, Trondheim, Norway, and Karolinska Institute, Stockholm, Sweden

- MD Anderson Cancer Center, Houston, TX, USA

- Sussex Cancer Research Centre, Brighton-Sussex Medical School, UK

- University of Oxford, UK

- Barts Cancer Institute, Queen Mary University of London, UK

- University of Twente, The Netherlands

- University of Southampton, UK

The tumour microenvironment (TME) has a fundamental role in supporting tumour growth and progression. The TME develops together with the tumour, and this development is regulated by complex intercellular communication between tumour cells and a diverse population of cellular components, including immune cells, fibroblasts and endothelial cells. The extensively studied tumour associated macrophages, cancer associated fibroblasts and fibrous protein network (the extracellular matrix) within the TME provide potent tumour support by promoting tumour cell viability, invasion and migration, and facilitating metastatic spread. The TME also contributes to chemo- and immunotherapy resistance. Depriving the tumour of its support by inhibiting pro-tumour mechanisms and communication routes within the TME is considered an important approach to suppress tumour growth and metastasis.

Recent advances in molecular technology, including single cell sequencing and spatial omics have provided unparalleled insights into the complexity of the TME.

This meeting will discuss the latest developments in TME research, focusing on the diverse subsets and spatial distribution of immune cells and fibroblasts, tumour promoting functions and mechanistic details of targeted inhibition of the TME.

The meeting will also provide a platform to align recent developments in TME research with clinical demands for new predictive and prognostic tumour markers and therapeutic targets for effective treatment of cancer patients. The increasing global cancer incidence makes the analysis of the TME an imperative task.

Abstract Submission

For delegates interested in presenting a poster during the conference, please submit abstracts (max. 300 words) post-registration to [email protected] for consideration.

Fees

Registration includes attendance on both conference days, plus lunch and tea/coffee breaks on both days. Optional booking for the conference dinner on Monday 21st October is available for an additional fee. Early bird discounted rate is available up to 23:59 on 31st August 2024.

If any delegates wish to bring a "plus one" attendee for the conference dinner or any other non-talk part of the meeting, then we have some limited capacity to accommodate this for an additional fee. Please contact the organising comitte via email ([email protected]) to discuss such potential arrangements following your registration.

Accommodation

VisitBrighton is the official accommodation booking provider for the Brighton Tumour Microenvironment Conference 2024, and we are delighted to offer specially negotiated accommodation rates for attendees. To book accommodation using this service, please visit our dedicated booking site .

The booking site will be open for bookings until 13th October 2024 but we advise early booking in order to guarantee your preferred hotel. Please note that the secured allocation of bedrooms at the conference rate at the Leonardo Royal Hotel Brighton Waterfront are bookable until the 9th September.

If you have any queries about accommodation or require assistance with booking your room please contact the Accommodation Bureau via [email protected].

Cancellation Policy

Delegates may cancel their registration and receive a full refund (minus booking fees) up until 7th October 2024. All requests for cancellation must be made through direct contact with the organising comittee via email ([email protected]). Any requests for cancellation made after this date will not be eligible for refund.

The organising comittee are not liable for any travel or accommodation expenses lost in the event of cancellation.

Dr Annamaria Gal - University of Brighton, UK

Dr Jimi Adu - University of Brighton, UK

Dr William Jones - University of Sussex, Brighton, UK

Professor Andrea Pepper - Brighton and Sussex Medical School, Brighton, UK

Joanna Godden - Sussex Cancer Fund

Sarah Ralphson - Sussex Cancer Fund

David Witham - Sussex Cancer Fund

Host or Publisher Dr Annamaria Gal