November APEx Seminar - Prof Linsday Bearne

November APEx Seminar - Professor Lindsay Bearne

Talk Title: Developing equitable rehabilitation interventions for people with peripheral artery disease

Abstract: Peripheral artery disease affects over 237 million adults globally. One common symptom of peripheral artery disease is intermittent claudication (ischaemic walking leg pain) although, it can lead to continuous pain, tissue loss and gangrene (chronic limb threatening ischaemia). Outcomes are poor; over half of those with symptomatic peripheral artery disease will die, have an amputation or cardiovascular event within five years of diagnosis. Recommended treatment for people with intermittent claudication includes supervised exercise therapy, but these hospital-based programmes are often not feasible to deliver nor acceptable to patients. New ways to support exercise participation are needed.

This presentation will describe the development of a home-based walking exercise behaviour change programme for people with intermittent claudication (the Motivating Structured Walking activity in Intermittent Claudication (MOSAIC1) programme) that aimed to improve mobility, function and quality of life in people with intermittent claudication. It will present the findings from a randomised controlled trial that evaluated MOSAIC1 and consider research inclusion in rehabilitation trials. Finally, it will describe new research that will co-design several community rehabilitation interventions with those who are most affected by peripheral artery disease and underrepresented communities.

Bio: Lindsay Bearne is Professor of Physiotherapy and Rehabilitation at City St George’s, University of London. She is a physiotherapist with experience from public, private and sports healthcare facilities in the UK and USA. Her research focuses on the impact of exercise and physical activity, community rehabilitation, and self-management interventions in adults with long term conditions. She works closely with patients, carers, and healthcare professionals to co-design complex rehabilitation interventions that can be implemented into practice. She leads several NIHR funded studies and the NIHR supported community rehabilitation research incubator hub. Alongside her academic role, until April 2025, she worked as a Senior Research Fellow in Knowledge Mobilisation and implementation science at the National Institute of Health and Care Research.

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