IMO Workshop 13: Treatment Revolution

Welcome to the registration page for the 13th Integrated Mathematical Oncology (IMO) workshop at the Moffitt Cancer Center. Now in its 13th year we are supported by our grant from the Cancer Systems Biology Consortium (CSBC) on the Delta Ecology of Non-Small Cell Lung Cancer and the Moffitt Cancer Center of Excellence for Evolutionary Therapy (CoE). The IMO workshop is designed to motivate and facilitate a hands-on modeling experience focused on developing innovative future generation cancer treatments - a treatment revolution. The workshop is comprised of both an educational event and competition and divides participants into multiple teams combining clinical, experimental and theoretical members. These teams integrate their energies to develop and implement a mathematical model focussed on the treatment revolution across a range of cancers. The teams are expected to come up with a model, solve it and give a presentation all within 4.5 intense days.

As always, we will have several independent judges to view both the specific aims and the closing presentations to decide the winning team. To facilitate integration and motivate participation we are offering an Amazon gift voucher to active participants of the winning team and to the runner up team. In addition, to facilitate further development of the winning project we are offering a $50K pilot grant (generously funded by Moffitt Cancer Center) to the leaders of the winning team.

As with last years workshop there will be a "speed dating for scientists" to break the ice among diverse group of participants on the 2nd. The opening presentation on the 3rd will summarize what is expected of the teams and serve to motivate the subsequent hands on model development sessions. We plan to have a separate poster session on the evening of the 3rd to allow participants to showcase their own research. Participation in the workshop requires registration in order to generate the teams and give numbers for the food and beverages we are providing throughout the workshop.

We are offering deluxe travel awards for external participation!!! Each award will cover flight + accommodation + meals for up to 6 nights and allow for both national and international scientists to participate in this unique hands on educational event. If you are either a PhD student, Postdoctoral student or junior faculty with a passion for research and a desire to better understand the role of cancer evolution in shaping therapeutic strategies as well as how to build integrated models then please apply during the registration process. Please note: the travel awards are even more limited than usual due to many people staying on after the MathOnco25 conference and will be offered on a competitive basis, so application does not guarantee participation. If you are able to cover your own expenses, please indicate this during the registration process.

Please note

TRAVEL AWARD APPLICATIONS WILL BE CLOSING ON Friday the 3rd of October 2024 at 5pm EST. AWARD WINNERS WILL BE CONTACTED before the 7th of October 2024.

What

Moffitt Cancer Center under the auspices of the Center for Evolutionary Therapy has been developing evolutionary therapies with the goal to control cancer rather than eradicate it. There has also been efforts to develop multistrike (or extinction therapies) that leverge the evolution informed combation and sequencing of drugs. Both of these efforts have led to clinical trials across a range of cancers.

Developing innovative treatment stratagies means thinking outside of the box and potentially doing things that might seem on the surface counterintutite but can actually have a positive impact on the long term. The theme of this workshop is treatment revolution which is all about taking risks, and going against the status quo to come up with the most innovative approaches to treating cancer. Potential theme that teams might tackle are:

(i)Exploiting the potential role of treatmet breaks

(ii) Integrating microenvironment modulating therapies

(iii) Using sparse and discrete data to facilitate treatment decisions

(iv) How best to exploit immunotherapy in combination with other drugs

(v) How can we model disease when quantifiable burden exists

When: Sunday, 6PM, 2nd November 2025 - Friday 2PM, 7th November 2025.

Where:

Speed dating: SRB Atrium, 6PM 2nd November.

Intoductory presentation: SRB Murphey, 9AM 3rd November.

Poster session: New World, 7PM 3rd November.

Working group sessions: Various rooms, 3rd November - 6th November.

Closing presentations: SRB Murphey, 9AM 7th November.

Chair and contact

The IMO Workshop is chaired and organized by the IMO Department Chair, Sandy Anderson. For more information concerning participation or about the workshop in general please contact IMO Department Assistant Danae Paris directly at Danae Paris.

Host or Publisher Integrated Mathematical Oncology