GBMSDG Winter Event - Untargeted Metabolomics - Dr. Clary Clish

Join us for the next Greater Boston Mass Spectrometry Discussion Group Event!

On February 26th, Dr. Clary Clish, Senior Director of the Metabolomics Platform at the Broad Institute of MIT and Harvard, will present on "Tools and Approaches for Nontargeted Metabolomics Studies of Disease in Human Cohorts."

📍 Location: Waters Immerse, 301 Binney St, Suite 102, Cambridge, MA 02142
📅 Date: February 26th

GBMSDG events are a great opportunity to learn about new mass spectrometry applications and network with the local MS community.

Special thanks to Waters for sponsoring the food, beverages, and event space!

Title: Tools and Approaches for Nontargeted Metabolomics Studies of Disease in Human Cohorts

Abstract: The potential of nontargeted metabolomics to detect and characterize early metabolic changes in subclinical disease has important implications for discovering pathophysiologic mechanisms and disease markers. Our lab has developed software tools and comprehensive LC-MS metabolomics methods that are suitably robust and informative to conduct large studies of biological specimens from human cohorts. Our work has included discovery of plasma metabolic signatures that indicate future risk of developing diabetes, cardiovascular disease, gastrointestinal cancer, and other conditions. Using examples from recent projects, this presentation will highlight approaches to acquiring nontargeted LC-MS metabolomics data, data processing and management using in-house developed tools, and approach and challenges associated with identification of unknowns.

Info: Presentation: Tools and Approaches for Nontargeted Metabolomics Studies of Disease in Human Cohorts

Host or Publisher Greater Boston Mass Spectrometry Discussion Group