Contemporary Methods in Medicinal Chemistry Symposium

This meeting will be hosted by Takeda in Cambridge, MA

Registration is required and ends at 11:30 PM on December 5, 2024

Thursday – December 12th, 2024

Takeda- 35 Lansdowne Street, Cambridge Massachusetts 02139

3:00 pm Welcome: Raj Rajur, Medicinal Chemistry Program Chair - CreaGen, Woburn, MA

3:10 pm - Introductory Remarks from Takeda

3:15 pm – 4:00 pm - Presentation: Michelle Garnsey - Pfizer

Title: "Discovery of SARS-CoV-2 papain-like protease (PLpro) inhibitors with efficacy in a murine infection model"

4:00 pm – 4:45 pm - Presentation: Derun Li - Nimbus

Title: "Designing Selective WRN Covalent Inhibitors from Non-Covalent Binders"

4:45 - 5:00 pm - Break

5:00 pm – 5:45 pm - Presentation: Brandon Vara – Merck

Title: "Discovery of MK-4424: a Potent, Exquisitely Selective, and CNS-penetrant RIPK1 Type-III Inhibitor to Treat Neurodegeneration"

5:45 pm - 6:30 pm - TBA

6:45 pm – 8:30 pm Dinner

THE PUBLIC IS INVITED - RESERVATIONS ARE REQUIRED

YOU MUST REGISTER IN ADVANCE TO ATTEND THE SYMPOSIUM: THERE IS NO REGISTRATION FEE TO ATTEND THE SYMPOSIUM, DINNER RESERVATIONS ARE REQUIRED.

Please use google map: 35 Lansdowne Street, Cambridge Massachusetts 02139.

MBTA closest stop is Central Square on the red line. Bus lines 1 and 2.

Parking is available at 10 Green St., directly across from the symposium entrance. Parking is free if validated at the entrance desk.

Attendees will need to enter via the back entrance to the building, which is located on Green St.

Registration or other questions? Please contact: Jaison by email at [email protected] or Raj Rajur [email protected]

Organizing Committee:

Mark Ashwell; Brian. Aquila; Blaise Lippa; Andrew Scholte; Peter Fuller; Michelle Lamb; Silvana Leit; Melissa Grenier-Davies; Paul Scola; Lauren Monovich; Jason Beiger; Paul Greenspan; Raj Rajur

Host or Publisher The Northeastern Section of the American Chemical Society