“BOTOX: Serendipity in Science”: Past, Present and Future of Botulinum Tox

We will also have the pleasure of the attendance of Dr. Mitchell Brin, SVP and Chief Scientific Officer of Neurotoxins (R&D, AbbVie) who is one of the pioneers and key developers of BOTOX, leading its research and clinical development since 1980s.

Abstract: The exponential growth of Botulinum Neurotoxins (BoNTs) for medical and aesthetic applications over the last few decades has led to a marked increase in the number of available BoNT products. As the popularity of neurotoxins increases, so are the challenges with respect to molecular architecture, intrinsic properties, pharmacological activity and manufacturing. This keynote is focused on tracing the birth and progress of neurotoxins, current challenges, and future opportunities.

Biography: Sathya has a PhD in “DARPin Folding and Stability” from University of Zurich, Switzerland and postdoc in “Molecular Chaperons Structure and Function” from Stanford University, CA. Since then, she has developed deep expertise in the discovery and development of several high-quality biologics across a range of therapeutic areas from working at Boehringer-Ingelheim, J&J, Amgen, and most recently, AbbVie. She has more than 15 years of experience in biologics R&D with multiple patents and publications and has successfully led efforts delivering bispecific for severe asthma, agonistic and antagonistic antibodies for ocular diseases, bispecific and cell therapy for prostate cancer and finally engineered neurotoxins for aesthetics and therapeutics indications.

Location: This is a hybrid event presented virtually via Abbie Teams Account and in-person at the AbbVie Campus, Theater in RD2 Level1, 2525 Dupont Drive, Irvine, CA, 92612. Please see attached map and fill out emailed forms for on-site attendance.

Agenda: On-Site: Check-in, Networking and Refreshments from 3PM to 4PM PT. Presentations and Discussion will be from 4:00-5:30PM PT. Virtual via Teams: login will open at 3:45PM PT. There is a $20 fee for on-site attendees to cover the cost of refreshments, $15 for AAPS Members. $5 for Students and Retired.

Registration: You must register to receive the Teams link or email with the questionnaire to receive the QR code for on-site entrance. Due to limited seating, all AbbVie attendees must register as well. First come first served for on-site.

Please register by Noon, Monday, Feb 23.

Important Instructions for On-Site Attendees: you must complete and e-sign 3 forms for access to the AbbVie Irvine campus which you will receive by email 2-3 days prior to the presentation. The subject of the email will be "Here is your pass to sign-in at the Feb 26, 2026, SCPDG meeting at the AbbVie Irvine Campus". After completion of the forms, you will receive a QR code by email which must be shown to AbbVie security at the gate to enter the campus. Everyone MUST have their own unique QR code. Access to the campus will be denied without a QR code.

Parking: Enter the campus from Dupont Ave (GATE 1). Follow signage for "SCPDG Event" and Park in the MAIN PARKING STRUCTURE or adjacent open parking. Registration/Meeting Location: Theater, RD2, Level 1. Please collect your name tags at the registration table near the RD2 Theater. Once inside the Theater, you must be always escorted by an AbbVie staff.

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