Des Moines Comedy Events

Comedy events Happening Next in Des Moines, IA

That 1 Guy

1159 24th Street Des Moines IA 50311 24 Oct 2025
ENTERTAINMENT

Hocus Pocus Bingo | Des Moines, IA

VC + K | 520 East Grand Avenue Des Moines IA 50309 9 Oct 2025
BINGO

MN Jazz Vocalist Leslie Vincent - National Act!

1326 Walnut St, Des Moines, IA, United States, Iowa 50309 17 Oct 2025
ENTERTAINMENT

Trey Kennedy at Hoyt Sherman Place

Hoyt Sherman Place 4 Oct 2025

Gabriel Iglesias at Wells Fargo Arena - Des Moines

Wells Fargo Arena - Des Moines 19 Oct 2025

The Bomb Shelter Comedy Showcase

Beechwood Lounge 4 Oct 2025

Disenchanted! The Hit Musical Comedy

Temple for Performing Arts 14 Oct 2025
COMEDY

Eddie Griffin at Hoyt Sherman Auditorium

Hoyt Sherman Auditorium 17 Oct 2025
TRIPS-ADVENTURES

Eddie Griffin at Hoyt Sherman Place

Hoyt Sherman Place 17 Oct 2025
CONTESTS

Gabriel Iglesias

Casey's Center 18 Oct 2025
TRIPS-ADVENTURES

Anjelah Johnson Reyes at Hoyt Sherman Auditorium

Hoyt Sherman Auditorium 8 Nov 2025
TRIPS-ADVENTURES

Anjelah Johnson Reyes at Hoyt Sherman Place

Hoyt Sherman Place 8 Nov 2025
CALENDAR

Anjelah Johnson-Reyes: The Family Reunion Tour

Hoyt Sherman Place 8 Nov 2025
THEATRE USD 36 TO 156

The Toxhards w/ Fishbait

1159 24th Street Des Moines IA 50311 13 Nov 2025
PARTIES

Gabriel Iglesias at Casey's Center

Casey's Center 19 Oct 2025
TRIPS-ADVENTURES

Magic Mustache Club @ XbK

xBk Live 24 Oct 2025
MAGIC-SHOW USD 59

Paula Poundstone at Hoyt Sherman Auditorium

Hoyt Sherman Auditorium 7 Nov 2025

HOSTAGE SITUATION - Des Moines, IA (11/22/25)

Des Moines 22 Nov 2025
USD 25

Paula Poundstone at Hoyt Sherman Place

Hoyt Sherman Place 7 Nov 2025
TRIPS-ADVENTURES

DEATH BECOMES HER: MIMOSA MOVIE

3800 Merle Hay Rd, Ste 1300, Des Moines, IA, United States, Iowa 50310 5 Oct 2025
ENTERTAINMENT

Adam Sandler at Casey's Center

Casey's Center 4 Oct 2025

Trey Kennedy at Hoyt Sherman Auditorium

Hoyt Sherman Auditorium 4 Oct 2025

Murder Mystery Dinners

4025 Tonawanda Dr, Des Moines, IA, United States, Iowa 50312 14 Nov 2025
NONPROFIT

Comedian Janee "Cool" Harvey starring in 'Hot Flash'

1163 24th St, Unit B Des Moines IA 50311 9 Oct 2025
COMEDY

Bored Teachers Comedy Tour

Hoyt Sherman Place Theater 9 Oct 2025
COMEDY

Shut Up and Rap Vol. 2

Lefty's Live Music 9 Nov 2025
ART USD 11 TO 16

Heather McMahan at Hoyt Sherman Place

Hoyt Sherman Place 21 Nov 2025
TRIPS-ADVENTURES

The Counselors of Evil present Something Scary

1159 24th Street Des Moines IA 50311 14 Oct 2025
ENTERTAINMENT

Special Ticketed Event - Nick Offerman

Franklin Jr High Event Center 14 Oct 2025
ART

Hannah Berner at Hoyt Sherman Auditorium

Hoyt Sherman Auditorium 5 Dec 2025

Naughty Nerds Cabaret presents: Hex Appeal

1159 24th Street Des Moines IA 50311 15 Nov 2025
PARTIES

Bored Teachers Comedy Tour at Hoyt Sherman Place

Hoyt Sherman Place 10 Oct 2025
COMEDY

Red Riding Hood

831 42nd St, Des Moines, IA, United States, Iowa 50312 9 Jan 2026
TRIPS-ADVENTURES

Mike T "Probably Too Nice" EP Release w/ Cdisiac + FlySpace

1159 24th Street Des Moines IA 50311 10 Oct 2025
PARTIES

Hannah Berner at Hoyt Sherman Place

Hoyt Sherman Place 5 Dec 2025

Bored Teachers Comedy Tour at Hoyt Sherman Auditorium

Hoyt Sherman Auditorium 10 Oct 2025
COMEDY

Militarie Gun w/ Liquid Mike and Public Opinion

1159 24th Street Des Moines IA 50311 30 Oct 2025
ENTERTAINMENT

Adam Sandler

Casey's Center 5 Oct 2025
CONTESTS

Gabriel Iglesias

Wells Fargo Arena - IA 18 Oct 2025

Dinner Detective Des Moines October 24th Public Show

Embassy Suites by Hilton Des Moines Downtown (Des Moines, Iowa) 24 Oct 2025
COMEDY

Meredith Willson’s The Music Man

221 Walnut St, Des Moines, IA, United States, Iowa 50309 20 Mar 2026
MUSIC

Speakeasy Comedy W/ Liam Nelson

xBk Live 2 Nov 2025
COMEDY USD 13 TO 25

Eddie Pepitone

xBk Live 22 Oct 2025
CONTESTS

George Lopez at Hoyt Sherman Place

Hoyt Sherman Place 20 Feb 2026

Comedy Penthouse 7

Bash Events & Catering 23 Oct 2025
PERFORMANCES

Dog Man - The Musical

Des Moines Civic Center 30 Jan 2026
LIVE-MUSIC

Triple Espresso

Temple for Performing Arts 18 Nov 2025
COMEDY

Oscar Wilde Night at The Royal Mile

210 4th St, Des Moines, IA, United States, Iowa 50309 15 Oct 2025
ART

Celebrate! with Above + Beyond Cancer

Hilton Des Moines Downtown 13 Nov 2025
ART

Class Show + Chowdown Improv

1159 24th St, Des Moines, IA 50311-4331, United States 28 Oct 2025
WORKSHOPS

Anthony Koester at Hilton Downtown Des Moines

Hilton Des Moines Downtown 21 Nov 2025

Eddie Griffin

Hoyt Sherman Place 18 Oct 2025
CONTESTS

The Twilight Zone UnScripted

Temple for Performing Arts 17 Mar 2026
ART

Jeff Dunham Des Moines

Des Moines 29 Dec 2025
COMEDY

George Lopez

Hoyt Sherman Place Theater 19 Feb 2026
ART

Eddie Pepitone

xBk Live 24 Oct 2025
CALENDAR

Dog Man - The Musical at Des Moines Civic Center

Des Moines Civic Center 31 Jan 2026
LIVE-MUSIC

Eddie Pepitone

1159 24th Street Des Moines IA 50311 23 Oct 2025
COMEDY

Heather McMahan at Hoyt Sherman Auditorium

Hoyt Sherman Auditorium 21 Nov 2025
CALENDAR

Neva Dinova, Cowgirl Eastern, Jordan Burchel at Lefty's

2307 University Ave, Des Moines, IA 19 Nov 2025

Paula Poundstone

Hoyt Sherman Place Theater 6 Nov 2025
ART

A Drag Queen Christmas at Des Moines Civic Center

Des Moines Civic Center 25 Nov 2025

Anjelah Johnson-Reyes

Hoyt Sherman Place Theater 7 Nov 2025
ART

Hannah Berner

Hoyt Sherman Place Theater 4 Dec 2025
TRIPS-ADVENTURES

David Sedaris at Hoyt Sherman Place

Hoyt Sherman Place 21 Oct 2025
TRIPS-ADVENTURES

Brandon Lake with Franni Cash

Casey's Center 10 Oct 2025
TRIPS-ADVENTURES

Bert Kreischer

Wells Fargo Arena - IA 10 Dec 2025

Bert Kreischer

Casey's Center 10 Dec 2025
TRIPS-ADVENTURES

Paula Poundstone

Hoyt Sherman Place 8 Nov 2025
TRIPS-ADVENTURES

Parking Heather McMahan

Hoyt Sherman Place 22 Nov 2025
TRIPS-ADVENTURES

Hannah Berner

Hoyt Sherman Place 6 Dec 2025
TRIPS-ADVENTURES

Bert Kreischer at Wells Fargo Arena - Des Moines

Wells Fargo Arena - Des Moines 11 Dec 2025
TRIPS-ADVENTURES

Heather McMahan

Hoyt Sherman Place 22 Nov 2025
TRIPS-ADVENTURES

Heather McMahan

Hoyt Sherman Place Theater 20 Nov 2025
ART

Matt Fraser - Des Moines

Hoyt Sherman Place 14 Nov 2025
TRIPS-ADVENTURES

David Sedaris

Hoyt Sherman Place 22 Oct 2025
TRIPS-ADVENTURES

George Lopez

Hoyt Sherman Place 21 Feb 2026
TRIPS-ADVENTURES

David Sedaris at Hoyt Sherman Auditorium

Hoyt Sherman Auditorium 21 Oct 2025
TRIPS-ADVENTURES

Bert Kreischer

Wells Fargo Arena 12 Dec 2025

Anjelah Johnson-Reyes

Hoyt Sherman Place 9 Nov 2025
TRIPS-ADVENTURES

Parking Gabriel Iglesias

Wells Fargo Arena 20 Oct 2025
TRIPS-ADVENTURES

Gabriel Iglesias

Wells Fargo Arena 20 Oct 2025