Cape Girardeau Live Music Events

Underground Jazz: Ana Catharina

420 Broadway, Cape Girardeau, MO, United States, Missouri 63701 21 Nov 2025

Hot Chocolate Bar

31 N Main St, Cape Girardeau, MO, United States, Missouri 63701 5 Dec 2025

MUSIC Open Mic Night @ Roost **NO COVER**

39 N. Broadview Street, Cape Girardeau, MO, United States, Missouri 63701 12 Dec 2025

Dobbins Conservatory presents Twelfth Night

518 S. Fountain St, Cape Girardeau, MO, United States, Missouri 63703 20 Nov 2025

The Return of First Friday

426 Broadway Street, Cape Girardeau, MO, United States, Missouri 63701 5 Dec 2025

The Bowling Family in Cape Girardeau

Cape First 27 Feb 2026

Powerful Voices Open Mic Show - Live Music, Comedy, Poetry+ More!

Cape Girardeau 30 Oct 2025